Elaine Choung-Hee Lee
Associate Professor, Director of Research
Specialization: Molecular Biology and Applied Genetics
Postdoctoral Fellow, Mount Desert Island Biological Laboratory, Salisbury Cove, ME
Postdoctoral Fellow, Yale University School of Medicine, New Haven, CT
Ph.D., Helen Reynolds Outstanding Doctoral Student, University of Connecticut, Storrs, CT
M.A., Outstanding Master’s Student Research, University of Connecticut, Storrs, CT
B.S., Day of Pride Scholar (15 top scholars of ~4000 in class), University of Connecticut, Storrs, CT
Radom-Aizik S, Maresh CM, Haddad F, Cooper DM, Nugas C, Casa DJ, Apicella JM, DeMartini JK, Lee EC, Munoz CX, and Zaldivar FP. The Impact of Ironman Triathlon on Innate Immune Cell Numbers and Function. American College of Sports Medicine (ACSM) 2013 Conference.
Munoz CX, Lee EC, McDermott BP, Beasley KN, Yamamoto LM, Emmanuel H, Hom LL, Casa DJ, Armstrong LE, Kraemer WJ, and Maresh CM. Circulating and intracellular HSP72 responds acutely to cumulative exercise stress, heat stress, dehydration, and rehydration, and may be mediated by collective effects of multiple stress-specific transcription factors. Experimental Biology (EB) 2013 Conference.
Hom LL, Lee EC, Apicella JM, Wallace SD, Emmanuel H, Klau JF, Poh PY, Marzano S, Armstrong LE, Casa DJ, and Maresh CM. Eleven days of moderate exercise and heat exposure induces acclimation without significant HSP70 and apoptosis responses of lymphocytes in college-aged males. Cell Stress Chaperones. 2012 Jan;17(1):29-39. doi: 10.1007/s12192-011-0283-5. Epub 2011 Jul 28.
Lee EC and Strange K. GCN-2 dependent inhibition of protein synthesis activates osmosensitive gene transcription via WNK and Ste20 kinase signaling. Am J Physiol Cell Physiol. 2012 Dec 15;303(12):C1269-77. doi: 10.1152/ajpcell.00294.2012. Epub 2012 Oct 17.
Lee EC, Manion D, Ditano J, and Strange K. Neuronal regulation of systemic osmotic stress response mechanisms in C. elegans. Experimental Biology, April 2012.
Lee EC and Strange K. Osmosensitive gene expression in C. elegans is regulated by conserved signaling mechanisms that control protein translation initiation. Experimental Biology, April 2012. Selected as 1 of 6 finalists for Research Recognition Award, Cellular and Molecular Physiology Section (CaMPS), American Physiological Society
Lee EC. Comparative genomics of aging and stress adaptation, UConn Systems Genomics Institute initiative, Jackson Laboratory and UConn Joint Symposium, September 2012.
*Burkewitz K, *Choe K, Lee EC, Deonarine A, and Strange K. Proteostasis in C. elegans is maintained during extreme osmotic stress by reduced translation with resultant increases in molecular chaperone capacity. Experimental Biology, April 2012. * co-first authors
Burkewitz K, Choe KP, Lee EC, Deonarine A, and Strange K. Characterization of the proteostasis roles of glycerol accumulation, protein degradation and protein synthesis during osmotic stress in C. elegans. PLoS One. 2012;7(3):e34153. doi: 10.1371/journal.pone.0034153. Epub 2012 Mar 28.
MDIBL Outstanding Mentor of the Year, 2012
Helen Reynolds Outstanding Doctoral Student Award, 2009
Oustanding Master’s Student Research Award, 2005
Day of Pride Scholar 1998-2002
NCAA and Big East Scholar Athlete Awards, 1999-2002
American Physiological Society, Cellular and Molecular Physiology Section
American Physiological Society, Exercise and Environmental Physiology Section
International Society of Exercise and Immunology
American College of Sports Medicine
National Strength and Conditioning Association
American Heart Association
In the News:
Happiness in a Glass. Redbook, June 2012, page 170